Preisgekrönte Forschungsarbeiten

myAIM sammelt herausragende Arbeiten im Gebiet der Allgemeinen Inneren Medizin. Diese werden regelmässig in einem Newsletter an die registrierten Nutzer von myAIM verschickt und tragen so zu deren Bekanntheit bei. Berücksichtigt werden Arbeiten aus der Schweiz, welche mit einem Forschungspreis ausgezeichnet wurden. Über die Aufnahme eingereichter Arbeiten in die Rubrik "Preisgekrönte Forschungsarbeiten AIM" sowie in den Newsletter entscheidet die myAIM-Redaktion.

Adjunct prednisone therapy for patients with community-acquired pneumonia - a randomized, placebo-controlled multicenter trial

Claudine Blum, Nicole Nigro, Matthias Briel, Philipp Schuetz, Elke Ullmer, Isabelle Suter-Widmer, Bettina Winzeler, Roland Bingisser, Hanno Elsässer, Daniel Drozdov, Birsen Arici, Sandrine Urwyler, Julie Refardt, Philip Tarr, Sebastian Wirz, Robert Thomann, Christine Baumgartner, Hervé Duplain, Dieter Burki, Werner Zimmerli, Nicolas Rodondi, Beat Mueller and Mirjam Christ-Crain
Fragestellung
We assessed whether short-term corticosteroid treatment reduces time to clinical stability in patients admitted to hospital for community-acquired pneumonia.
Ergebnis
Prednisone treatment for 7 days in patients with community-acquired pneumonia admitted to hospital shortens time to clinical stability without an increase in complications.

SGIM-Award 2015 for best publication


Mortality risk prediction in COPD by a prognostic biomarker panel

Mortality risk prediction in COPD by a prognostic biomarker panel
Fragestellung
COPD is a complex disease with varying phenotypes. The simultaneous determination of multiple biomarkers reflecting different pathobiologic pathways could be useful in identifying individuals with increased risk of death.
Ergebnis
Simultaneously elevated levels of adrenomedullin, arginine vasopressin and atrial natriuretic peptide are associated with increased risk of death in patients with stable COPD.

Viollier Award 2015 for best publication


Predicting recurrence in elderly patients with unprovoked venous thromboembolism: prospective validation of the updated Vienna Prediction Model

Tobias Tritschler, Marie Méan, Andreas Limacher, Nicolas Rodondi, Drahomir Aujesky
Fragestellung
Is there an association between D-dimer levels and venous thromboembolism recurrence in elderly patients.
Ergebnis
We observed a significant association between quantitative D-dimer levels and recurrentVTE. However, D-dimer was not useful in predicting recurrent VTE using the usual test cut-off value (500 µg/L).

SGIM-Award 2015: 1st prize of best free communication


Impact of case management on frequent users' quality of life: a randomized, controlled trial

Katia Iglesias, Karine Moschetti, Stéphanie Baggio, Venetia Velonaki, Ornella Ruggeri, Olivier Hugli, Bernard Burnand, Jean-Blaise Wasserfallen, Jean-Bernard Daeppen, Patrick Bodenmann
Fragestellung
The aim of this study was to examine to what extent a case management intervention in a emergency department (ED) improved frequent ED users' quality of life.
Ergebnis
The case management intervention was accompanied by improvement in frequent ED users' environment quality of life.

SGIM-Award 2015: 2nd prize of best free communication


Is thyroid dysfunction associated with anaemia?

Khadija M'Rabet-Bensalah, Michael Coslovsky, Christine Baumgartner, Tinh-Hai Collet, Wendy P. J. den Elzen, Robert Luben, Anne Angelillo-Scherrer, Drahomir Aujesky, Kay-Tee Khaw, Nicolas Rodondi
Fragestellung
The aim of this study is to seek a possible association between thyroid dysfunction and anaemia.
Ergebnis
Overt hypo- and hyperthyroidism, but not subclinical thyroid dysfunction, are associated with a higher prevalence of anaemia.

SGIM-Award 2015: 3rd prize of best free communication


"HOSPITAL" score predicts patients at high risk of potentially avoidable readmission: multicenter validation study in Switzerland

Jacques Donzé, Jérôme Stirnemann, Pedro Marques-Vidal, Drahomir Aujesky
Fragestellung
The “HOSPITAL” score, derived previously in the US, is an easy to use prediction model that accurately identify those medical patients at high risk of potentially avoidable readmission. In order to test its generalizability in Switzerland, we aimed to externally validate the “HOSPITAL” score in a multicenter study.
Ergebnis
The “HOSPITAL” score identified patients at high risk of 30-day potentially avoidable readmission with fair discrimination when applied to a large multicenter cohort of medical patients in Switzerland.

Novartis-Award 2015: 1st prize of best poster at the SGIM congress 2015


NEDD4 promotes cell growth and migration through PTEN/PI3K/AKT signaling pathway in hepatocellular carcinoma

Ewelina Biskup, Xiao Yu Yang, Zhi Jun Huang, Jun Jun Zhi
Fragestellung
The study aimed to investigate the role of NEDD4 as an oncoprotein by targeting the tumor suppressor PTEN (phosphatase and tensin homolog) in hepatocellular carcinoma cells.
Ergebnis
Our results indicate that NEDD4 plays a critical role in activating PTENPI3K/AKT signaling pathway, which promotes HCC cells proliferation and metastasis.

Novartis-Award 2015: 2nd prize of best poster at the SGIM congress 2015


Physical activity and energy expenditure across occupational categories

Stefanie Zogg, Jonas Mundwiler, Ulla Maarit Schüpbach-Siira, Thomas Dieterle, David Miedinger, Jörg Leuppi
Fragestellung
The aim of this study was to investigate energy expenditure, daily steps and physical activity in Swiss employees during work and leisure-time in relation to their aerobic capacity.
Ergebnis
In a representative sample of a working population we found that blue-collar workers had higher levels of occupational activity and aerobic capacity, while leisure-time activity did not differ between groups. These findings suggest that subjects in low physically demanding jobs do not compensate sufficiently for their inactivity at work, while aerobic capacity appears to be predominantly depending on work activity rather than on leisure-time activity.

Novartis-Award 2015: 3rd prize of best poster at the SGIM congress 2015


Prescription of hypnotics during hospital stay: An epidemiological study in a Swiss hospital

Laurence Schumacher, Anne-Laure Blanc, Damien Tagan, Annelore Sautebin, Nicolas Widmer
Fragestellung
This study aims to describe introduction and discharge prescription of hypnotic drugs during stay in an internal medicine ward.
Ergebnis
Introduction of a hypnotic medication happened in nearly 40% of hospitalized patients. Most of the time, physicians reassessed the new hypnotic on discharges prescriptions, one-third of hypnotics are kept at the end of the hospital stay.

Novartis-Award 2015: 3rd prize of best poster at the SGIM congress 2015

Initiatoren

jhas swiss-young-internists SGAIM - Schweizerische Gesellschaft für Allgemeine Innere Medizin

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